D9775

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D9775

Sigma

 

N,N-Dimethyldodecylamine N-oxide

≥99% (titration)

Synonym:DDAO, Lauryldimethylamine N-oxide, LDAO
CAS Number:1643-20-5
Linear Formula:CH3(CH2)11N(O)(CH3)2
Molecular Weight:229.40
Beilstein Registry Number:1769927
EC Number:216-700-6
MDL number:MFCD00002049

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Description

ApplicationDDAO is a non-denaturing zwitterionic surfactant with a critical micelle concentration (CMC) or approximately 1 mM. It is used to solubilize proteins and to study the conformation and molecular interactions of macromolecules.

Properties

assay≥99% (titration)
mp132-133 °C(lit.)
storage temp.2-8°C

Safety

Personal Protective EquipmentEyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Hazard CodesC
Risk Statements34
Safety Statements26-36/37/39-45
RIDADRUN3259 8/PG 2
WGK Germany2
RTECSJR6650000

References

referenceLair, V., et al., Thermodynamic study of the protonation of dimethyldodecylamine N-oxide micelles in aqueous solution at 298 K. Establishment of a theoretical relationship linking critical micelle concentrations and pH. Langmuir 20, 8490-8495, (2004)
 Yildiz, O., et al., Structure of the monomeric outer-membrane porin OmpG in the open and closed conformation. EMBO J. 25, 3702-3713, (2006)
 Yanagi, K., et al., Local electrostatic field induced by the carotenoid bound to the reaction center of the purple photosynthetic bacterium rhodobacter sphaeroides. J. Phys. Chem. B 109, 992-998, (2005)
 Kocherbitov, V., and Soderman, O., Hydration of dimethyldodecylamine-N-oxide: Enthalpy and entropy driven processes. J. Phys. Chem. B 110, 13649-13655, (2006)
 Richter, M.F., et al., Single-molecule spectroscopic characterization of light-harvesting 2 complexes reconstituted into model membranes. Biophys. J. e-pub Apr. 6, (2007)
BeilsteinBeil. 4,IV,798
 Corp MSDS 1 (1), 1371:B / FT-IR 2 (1), 474:C / RegBook 1 (1), 323:I / Sax 6, 1158 / Structure Index 1, 50:C:3